A Hybrid Approach to Cardiac Resynchronization Therapy

A hybrid approach to cardiac resynchronization therapy.

BACKGROUND CRT (atrial-synchronized bi-ventricular pacing) has been shown to significantly improve the quality of life and exercise tolerance in patients with moderate-severe heart failure and an interventricular conduction delay (>120 msec) when compared to controls. Traditionally it has been performed by cardiologists in electrophysiology laboratories. In the event that the left ventricular l...

Superresponse to cardiac resynchronization therapy.

C ase presentation: A 55-year-old female patient underwent implan-tation of a cardiac resynchronization therapy (CRT) defibrillator 6 years ago owing to nonischemic dilated cardio-myopathy. Her left-ventricular (LV) ejection fraction (EF) was 28% before implantation, her LV end-diastolic volume index (EDVI) was 144 mL/m 2 , and her LV end-systolic volume index (ESVI) was 104 mL/m 2. Her intrins...

Cardiac Simulation to Personalize Cardiac Resynchronization Therapy.

Cardiac-resynchronization therapy.

Cardiac resynchronization therapy (CRT) addresses abnormal left ventricular (LV) activation that produces detrimental effects on cardiac systolic and diastolic function. CRT improves symptoms and ventricular performance, promotes reverse remodeling, and decreases mortality and hospitalization in patients with congestive heart failure (CHF). Atrial-synchronized biventricular stimulation reverses...

Cardiac Resynchronization Therapy

According to the 2013 update on heart disease statistics from American Heart Association, an estimated 5.1 million Americans ≥20 years of age have a diagnosis of heart failure. In the year 2009, heart failure was noted to be the primary cause of death in >56 000 people and contributed to death of >274 000 people. It is one of the most common causes of hospitalization in patients ≥65 years of ag...